Dear Colleagues
I hope you all are doing well. In the November newsletter I hope to bring you the results of some of the pro ballplayers taking LuRong Supreme (Mid American 1-800-922-1744). There are 3 testimonials from them listed on the supreme nutrition website and results have been very encouraging. Even though it is 100% legal with no short or long term side effects- professional athletes should inform their prospective licensing agencies they are taking it because it can naturally raise depressed IGF-1 levels (which is a very good thing).
In this newsletter I wanted to talk about an easy AK procedure I have been doing that I find interesting as well as a few other tidbits and then turn it over to my son Noah who was at a medical research lab over the summer. His experiment there was pretty amazing.
Clinical Tidbits
In AK there is an old test (I am not sure who developed it) that I have used to get a rough idea of cardiac function. We test the person’s subscapularis in a standing position and then have them do 10 jumps and retest. In patients who then show a weakening we find that it is often negated by the heart NL and L-Carnitine (Thorne 1-800-228-1966). I always view these patients as having an elevated cardiac risk.
Recently I have added a 2nd test that I thought might assess circulatory issues. With the patient supine, we take a strong indicator muscle and have the person rotate their head all the way to the right and test the muscle and then all the way to the left and test. Assuming the muscle stays strong both ways (or else there may be cervical or other structural issues), we have them repeat it but after turning it to the right and testing, we then keep the neck in that position and test again after 10 seconds in that position. In some patients it weakens and most often the weakness is negated by Perfusia (Thorne). We also do it with left rotation. I have found this test positive quite often in patients at high risk for cardiac issues. After taking the supplements for a few weeks they usually pass the test and I personally believe we have decreased their risk. Of course you should consider referral to a cardiologist and should be careful about osseous cervical adjustments in these patients.
My Son’s summer research project on Ovarian Cancer
My name is Noah Lebowitz and I am going into my senior year at Arizona State University as a biology major. This summer I had an internship in the OBGYN reproductive immunology and ovarian cancer lab of Dr. Gil Mor, MD/PhD at Yale University in New Haven, CT. One day at the lab they drew my blood, mixed it with ovarian cancer stem cells (OCSCs), and then checked for different amounts of an OCSC marker, CK18. They attempted this twice on me, but both times it came back negative (while it did work on the other people in the lab). I realized most likely my blood wasn’t the cure for cancer, and wondered why this had occurred. Something stopped the cancer cells from growing in my blood but not in the other workers blood. Living in Connecticut for 8 weeks I was taking Morinda Supreme (3 pills 1-2x day) as a prophylaxis against developing a fungal problem from mold in the environment there and as an overall immune system booster. I knew how morinda was a strong antifungal/parasitic/viral, etc. and wondered if morinda also had anti-cancer activity.
After searching I found an article, Horknick, Conrad A, et al. Inhibition of angiogenic initiation and disruption of newly established human vascular networks from Morinda Citrifolia (noni), 2003. The article talked about morinda acting as an anti-angiogenic agent in breast cancer veins as well as placental vein implants. Cancer tumors can be highly angiogenic, the main way that a tumor is able to metastasize. I hypothesized that if morinda could block angiogenesis in breast cancer vein implants, then possibly it was destroying the OCSCs they mixed in my blood.
To test this hypothesis we took sets of 96 well plates and filled 48 in one plated with ovarian cancer cells, and the other plate with ovarian cancer stem cells. In each plate we had 12 control wells (no treatment). Morinda Supreme (Mid American 1-800-922-1744) was dissolved in ethanol for all treatments. The highest treatment for the ovarian cancer cells was .04 mg/mL (approximately the same concentration as a person taking 1/3 of a capsule), and a 5 fold dilution factor was used for 5 other treatment groups (.008, .0016, etc). The cells were treated and then observed in Incucyte (an incubator with a camera that took pictures of each well every 3 hours) over a five day period.
In the ovarian cancer cells treated with Morinda, over the first 50 hours approximately 50% of the cells underwent apoptosis for the three most concentrated treatment groups. The control group on the other hand, increased nearly 900%, and the two lowest concentration treatment groups did increase, but not nearly as much as the control (see graph 1 below, only 3 groups shown for visual clarity). A video of the treatment shows the cells in the highest concentration Morinda group undergoing apoptosis as time went by.
After the 120 hours a cell titer assay was run to check for cell viability and is graphed below (graph 2). As you can see there was a 52% decrease in cancer cells treated with Morinda compared to a 900% increase in cancer cells in the control group. We can’t draw any specific conclusions but the decrease in cancer cells compared to controls makes a powerful statement.
If you think of chemotherapy drugs, they are immune system suppressors. Morinda is a known immune system booster. With this in mind, theoretically en vivo experiments with morinda could have an even great anti-cancer result then in vitro experiments.
The ovarian cancer stem cells showed a different response to morinda (these cells are usually chemoresistant). The highest treatment group (.02 mg/mL) decreased in cell population over the first 40 hours approximately 30% until growing to 130% of the original size. All other treatment groups (and the controls) increased 300% (over the first 40 hours while the highest treatment decreased, the control increased approximately 100%).
Graph 1 . The cell growth was graphed using density calculations from Incucyte. The .04, .008. and .0016 mg/mL treatment groups decreased their cell growth (cell death/apoptosis) by approx. 52%. The two lowest concentration treatment groups increased 500 and 600%, while the no treatment groups increased 750 and 900%. Only 3 results are graphed for visual clarity.
Graph 2. The cell viability was graphed after running a cell titer assay. No treatment should show a value close to one (meaning 100% of the cells are alive), while a value of 0 constitutes all cells are dead. The lowest treatment (.0000064 mg/mL) was close to 1, while the highest treatment group (.04 mg/mL) was approx 0.2, meaning not many cells are still living.
We can not draw any conclusions on how well Morinda can perform as a cancer treatment but if this was not an all natural unrefined (except for dried and powdered) substance- the professors would be quite excited and doing all kinds of follow ups. We can conclude that it wouldn’t be a bad idea to try Morinda if you have a depressed immune system or to add it to your physician prescribed treatments (with their approval) if you have a life threatening disease.
HD Syndrome
After writing about solanine toxicity syndrome and methylxanthine toxicity syndrome I have found that there definitely is a % of non compliant patients. For methylxanthines we usually need 3-4 weeks of strict compliance. For solanines 1 month minimum, but some patients need indefinite avoidance.
Back in the 1980’s I had a 50 year old patient Helen D. When she first presented, she could only walk a maximum of about 30 feet because of severe arthritis. She was on 8 prescription medications. After some dietary recommendations, supplements etc., within 6 weeks she was walking 2 miles daily and she no longer needed any of the prescriptions (I worked with a local MD). After continuing on the program for another month or so she decided she would rather eat the way she used to even if it meant going back to her old health status and symptoms (which ended up happening shortly thereafter). This case has always stuck in my mind. I realized that all we can do in some cases is present the information and the patient’s compliance is up to his/her free will. Sometimes when they go off the program the symptoms are severe enough that it is a powerful motivation to go back on and be strict. For instance a patient told me yesterday that whenever they put chocolate back in she finds it extremely painful to walk and thus is motivated to stay off of it. Dealing with solanines and methylxanthines in patients sensitive to them can be challenging - they are powerful naturally occurring chemicals with addictive properties. We can lessen the deleterious effects with Body Guard Supreme, Takesumi, Thera Supreme, Basic B Complex (If you haven’t read the papers they are on my website) but simultaneous avoidance will optimize results.
It is our job to lay out the information and then up to the patients to be compliant. Even though Helen D’s case was in a way heart breaking, it was her choice.
Available Info/Products, etc.
1.DVD- Treating The Complex Patient 2009: This DVD seminar, approximately 6 hours long will teach the physician a simple to apply, effective protocol to treat patients with chronic fatigue, allergies, chemical sensitivities, intestinal dysbiosis, (fungal, bacterial, parasitic, and viral infections), food sensitivities, altered intestinal permeability, toxic metal problems, endocrine dysfunction, nutritional imbalances, chronic pain and subluxations. Knowledge of basic muscle testing is helpful. A complete protocol is taught that you can use to treat even the most chronic patients. The 4 DVD set is suited for both the novice and the advanced practitioners in our work and has many changes from previous DVD’s. A complete set of advanced notes accompanies the dvd set. This dvd set supersedes our previous ones. The price is $250 and can be paid by check to our office or paypal to noach2343@aol.com. There is a paypal link on our website www.michaellebowitzdc.com to pay.
2. Clinical Indications of Thorne Research Products: This handout has both academic and clinical observations on well over 100 products I use in my office. Approximately 65% of the products I use are by Thorne Research. Reasons are given. This handout is free and is available in written form or on CD-Rom. You may either call our office for a copy or download it from our website: www.michaellebowitzdc.com as you can download it.
Clinical Indications of Supreme Nutrition Products can also be downloaded from our website or obtained by calling Mid American Marketing 1-800-922-1744.
3. Personal Seminars with Dr. Lebowitz: Dr. Lebowitz teaches seminars to one or two doctors at a time in his home/office in Grand Junction, CO. These classes are tailored to meet your individual needs and can be as basic or advanced as you would like. Treatment for you and/or your family can be included in the teaching. Colorado continuing education hours can be provided. Best days are Sundays or Mondays. Call to schedule exact dates. Cost is $300 for one physician or $500 for 2 physicians coming together.
4. Test Kits for Dr. Lebowitz protocol. Call AK Test Kits at 1-888-323-0625 or see our website http://www.michaellebowitzdc.com for more details. Info is also available on CD-Rom. These new kits will greatly simplify and speed up your testing making you more efficient and accurate in patient assessment.
5. Lasers we use in our protocol (rectangular beam output 635nm 5mw) Laseronix 1-808- 879-9391. The one we use is called “the Desensitizer”.